Mice with cardiac overexpression of PPARγ have impaired repolarization and spontaneous fatal ventricular arrhythmias (Morrow, PPARγ overexpression induces fatal arrhythmias)

BACKGROUND: Diabetes and obesity, which confer an increased risk of sudden cardiac death, are associated with cardiomyocyte lipid accumulation and altered cardiac electrical properties, manifested by prolongation of the QRS duration and QT interval. It is difficult to distinguish the contribution of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Morrow, John P., Katchman, Alexander, Son, Ni-Huiping, Trent, Chad M., Khan, Raffay, Shiomi, Takayuki, Huang, Haiyan, Amin, Vaibhav, Lader, Joshua M., Vasquez, Carolina, Morley, Gregory E., D'Armiento, Jeanine, Homma, Shunichi, Goldberg, Ira J., Marx, Steven O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258098/
https://ncbi.nlm.nih.gov/pubmed/22124376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.056309
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados