Cardiomyocyte-specific Loss of Diacylglycerol Acyltransferase 1 (DGAT1) Reproduces the Abnormalities in Lipids Found in Severe Heart Failure

Diacylglycerol acyltransferase 1 (DGAT1) catalyzes the final step in triglyceride synthesis, the conversion of diacylglycerol (DAG) to triglyceride. Dgat1(−/−) mice exhibit a number of beneficial metabolic effects including reduced obesity and improved insulin sensitivity and no known cardiac dysfun...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Li, Trent, Chad M., Fang, Xiang, Son, Ni-Huiping, Jiang, HongFeng, Blaner, William S., Hu, Yunying, Yin, Yu-Xin, Farese, Robert V., Homma, Shunichi, Turnbull, Andrew V., Eriksson, Jan W., Hu, Shi-Lian, Ginsberg, Henry N., Huang, Li-Shin, Goldberg, Ira J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Lipids
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207999/
https://ncbi.nlm.nih.gov/pubmed/25157099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601864
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