What are Nuclear Receptor Ligands?

Por Sladek, Frances M.
Publicado em 2010

The yin and yang of proliferation and differentiation: Cyclin D1 inhibits differentiation factors ChREBP and HNF4α

Por Sladek, Frances M.
Publicado em 2012

Nuclear Receptor Hepatocyte Nuclear Factor 4α1 Competes with Oncoprotein c-Myc for Control of the p21/WAF1 Promoter

Por Hwang-Verslues, Wendy W., Sladek, Frances M.
Publicado em 2008

HNF4α -- role in drug metabolism and potential drug target?

Por Hwang-Verslues, Wendy W., Sladek, Frances M.
Publicado em 2010

HNF4α: a new biomarker in colon cancer?

Por Chellappa, Karthikeyani, Robertson, Graham R, Sladek, Frances M
Publicado em 2012

Competitive Cofactor Recruitment by Orphan Receptor Hepatocyte Nuclear Factor 4α1: Modulation by the F Domain

Por Ruse, Michael D., Privalsky, Martin L., Sladek, Frances M.
Publicado em 2002

Prevalence of the Initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promoters

Por Yang, Chuhu, Bolotin, Eugene, Jiang, Tao, Sladek, Frances M., Martinez, Ernest
Publicado em 2006

Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors

Por Fang, Bin, Mane-Padros, Daniel, Bolotin, Eugene, Jiang, Tao, Sladek, Frances M.
Publicado em 2012

Modulation of Transcriptional Activation and Coactivator Interaction by a Splicing Variation in the F Domain of Nuclear Receptor Hepatocyte Nuclear Factor 4α1

Por Sladek, Frances M., Ruse, Michael D., Nepomuceno, Luviminda, Huang, Shih-Ming, Stallcup, Michael R.
Publicado em 1999

Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs

Por Allevato, Michael, Bolotin, Eugene, Grossman, Mark, Mane-Padros, Daniel, Sladek, Frances M., Martinez, Ernest
Publicado no PLoS One (2017)

Nuclear Receptor HNF4α Binding Sequences are Widespread in Alu Repeats

Por Bolotin, Eugene, Chellappa, Karthikeyani, Hwang-Verslues, Wendy, Schnabl, Jake M, Yang, Chuhu, Sladek, Frances M
Publicado em 2011

Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver

Por Deol, Poonamjot, Evans, Jane R., Dhahbi, Joseph, Chellappa, Karthikeyani, Han, Diana S., Spindler, Stephen, Sladek, Frances M.
Publicado no PLoS One (2015)

Conservation of DNA and Ligand Binding Properties of Retinoid × Receptor from the Placozoan Trichoplax adhaerens to human

Por Reitzel, Adam M., Macrander, Jason, Mane-Padros, Daniel, Fang, Bin, Sladek, Frances M., Tarrant, Ann M.
Publicado no J Steroid Biochem Mol Biol (2018)

MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300

Por Li, Qi-Jing, Yang, Shen-Hsi, Maeda, Yutaka, Sladek, Frances M., Sharrocks, Andrew D., Martins-Green, Manuela
Publicado em 2003

Hepatocyte Nuclear Factor 4α Is Essential for Embryonic Development of the Mouse Colon

Por Garrison, Wendy D., Battle, Michele A., Yang, Chuhu, Kaestner, Klaus H., Sladek, Frances M., Duncan, Stephen A.
Publicado em 2006

Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver

Por Battle, Michele A., Konopka, Genevieve, Parviz, Fereshteh, Gaggl, Alexandra Lerch, Yang, Chuhu, Sladek, Frances M., Duncan, Stephen A.
Publicado em 2006

Integrated Approach for the Identification of Human Hepatocyte Nuclear Factor 4α Target Genes Using Protein Binding Microarrays

Por Bolotin, Eugene, Liao, Hailing, Chi Ta, Tuong, Yang, Chuhu, Hwang-Verslues, Wendy, Evans, Jane R., Jiang, Tao, Sladek, Frances M.
Publicado em 2010

Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4α (HNF4α) gene

Por Maeda, Yutaka, Hwang-Verslues, Wendy W., Wei, Gang, Fukazawa, Takuya, Durbin, Mary L., Owen, Laurie B., Liu, Xuan, Sladek, Frances M.
Publicado em 2006

Down-Regulation of Hepatic HNF4α Gene Expression during Hyperinsulinemia via SREBPs

Por Xie, Xuefen, Liao, Hailing, Dang, Huaixin, Pang, Wei, Guan, Youfei, Wang, Xian, Shyy, John Y.-J., Zhu, Yi, Sladek, Frances M.
Publicado em 2009

Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor

Por Yuan, Xiaohui, Ta, Tuong Chi, Lin, Min, Evans, Jane R., Dong, Yinchen, Bolotin, Eugene, Sherman, Mark A., Forman, Barry M., Sladek, Frances M.
Publicado em 2009