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Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor
Orphan nuclear receptors have been instrumental in identifying novel signaling pathways and therapeutic targets. However, identification of ligands for these receptors has often been based on random compound screens or other biased approaches. As a result, it remains unclear in many cases if the rep...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680617/ https://ncbi.nlm.nih.gov/pubmed/19440305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005609 |
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