Chargement en cours...
Potent synthetic and endogenous ligands for the adopted orphan nuclear receptor Nurr1
Until recently, Nurr1 (NR4A2) was known as an orphan nuclear receptor without a canonical ligand-binding domain, featuring instead a narrow and tight cavity for small molecular ligands to bind. In-depth characterization of its ligand-binding pocket revealed that it is highly dynamic, with its struct...
Enregistré dans:
| Publié dans: | Exp Mol Med |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8080818/ https://ncbi.nlm.nih.gov/pubmed/33479411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-021-00555-5 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|