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Hunting for the function of orphan GPCRs – beyond the search for the endogenous ligand
Seven transmembrane-spanning proteins (7TM), also called GPCRs, are among the most versatile and evolutionary successful protein families. Out of the 400 non-odourant members identified in the human genome, approximately 100 remain orphans that have not been matched with an endogenous ligand. Apart...
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| Udgivet i: | Br J Pharmacol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley & Sons, Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500361/ https://ncbi.nlm.nih.gov/pubmed/25231237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12942 |
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