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Identifying ligands at orphan GPCRs: current status using structure‐based approaches
GPCRs are the most successful pharmaceutical targets in history. Nevertheless, the pharmacology of many GPCRs remains inaccessible as their endogenous or exogenous modulators have not been discovered. Tools that explore the physiological functions and pharmacological potential of these ‘orphan’ GPCR...
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| Veröffentlicht in: | Br J Pharmacol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341249/ https://ncbi.nlm.nih.gov/pubmed/26837045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13452 |
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