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MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300
CBP/p300 recruitment to enhancer-bound complexes is a key determinant in promoter activation by many transcription factors. We present a novel mechanism of activating such complexes and show that pre-assembled Elk-1–p300 complexes become activated following Elk-1 phosphorylation by changes in Elk-1–...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140103/ https://ncbi.nlm.nih.gov/pubmed/12514134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg028 |
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