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Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs
The MYC oncoprotein regulates transcription of a large fraction of the genome as an obligatory heterodimer with the transcription factor MAX. The MYC:MAX heterodimer and MAX:MAX homodimer (hereafter MYC/MAX) bind Enhancer box (E-box) DNA elements (CANNTG) and have the greatest affinity for the canon...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5515408/ https://ncbi.nlm.nih.gov/pubmed/28719624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180147 |
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