Bioinformatic Description of Immunotherapy Targets for Pediatric T-Cell Leukemia and the Impact of Normal Gene Sets Used for Comparison

Por Orentas, Rimas J., Nordlund, Jessica, He, Jianbin, Sindiri, Sivasish, Mackall, Crystal, Fry, Terry J., Khan, Javed
Publicado em 2014

Paired Expression Analysis of Tumor Cell Surface Antigens

Por Orentas, Rimas J., Sindiri, Sivasish, Duris, Christine, Wen, Xinyu, He, Jianbin, Wei, Jun S., Jarzembowski, Jason, Khan, Javed
Publicado no Front Oncol (2017)

The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas

Por Pemov, A, Li, H, Patidar, R, Hansen, NF, Sindiri, S, Hartley, SW, Wei, JS, Elkahloun, A, Chandrasekharappa, SC, Boland, JF, Bass, S, Mullikin, JC, Khan, J, Widemann, BC, Wallace, MR, Stewart, DR
Publicado no Oncogene (2017)

Germline CARD11 mutation in a patient with severe congenital B cell lymphocytosis

Por Brohl, Andrew S., Stinson, Jeffrey, Su, Helen C., Badgett, Thomas, Jennings, Chester D., Sukumar, Gauthaman, Sindiri, Sivasish, Wang, Wei, Kardava, Lela, Moir, Susan, Dalgard, Clifton L., Moscow, Jeffrey A., Snow, Andrew L., Khan, Javed
Publicado no J Clin Immunol (2014)

Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma

Por Tenente, Inês M, Hayes, Madeline N, Ignatius, Myron S, McCarthy, Karin, Yohe, Marielle, Sindiri, Sivasish, Gryder, Berkley, Oliveira, Mariana L, Ramakrishnan, Ashwin, Tang, Qin, Chen, Eleanor Y, Petur Nielsen, G, Khan, Javed, Langenau, David M
Publicado no eLife (2017)

A Mutational Comparison of Adult and Adolescent and Young Adult (AYA) Colon Cancer

Por Tricoli, James V., Boardman, Lisa A., Patidar, Rajesh, Sindiri, Sivasish, Jang, Jin S., Walsh, William D., McGregor, Paul M., Camalier, Corinne E., Mehaffey, Michele G., Furman, Wayne L., Bahrami, Armita, Williams, P. Mickey, Lih, Chih-Jian, Conley, Barbara A., Khan, Javed
Publicado no Cancer (2017)

Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma

Por Hayes, Madeline N., McCarthy, Karin, Jin, Alexander, Oliveira, Mariana L., Iyer, Sowmya, Garcia, Sara P., Sindiri, Sivasish, Gryder, Berkley, Motala, Zainab, Petur Nielsen, G., Borg, Jean-Paul, van de Rijn, Matt, Malkin, David, Khan, Javed, Ignatius, Myron S., Langenau, David M.
Publicado no Cell Stem Cell (2018)

Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T Cell Receptors in High-risk MYCN-not-amplified Human Neuroblastoma

Por Wei, Jun S., Kuznetsov, Igor B., Zhang, Shile, Song, Young K., Asgharzadeh, Shahab, Sindiri, Sivasish, Wen, Xinyu, Patidar, Rajesh, Najaraj, Sushma, Walton, Ashley, Auvil, Jaime M. Guidry, Gerhard, Daniela S., Yuksel, Aysen, Catchpoole, Daniel, Hewitt, Stephen M., Sondel, Paul M., Seeger, Robert, Maris, John M., Khan, Javed
Publicado no Clin Cancer Res (2018)

Low mutation burden and frequent loss of CDKN2A/B and SMARCA2, but not PRC2, define premalignant neurofibromatosis type 1–associated atypical neurofibromas

Por Pemov, Alexander, Hansen, Nancy F, Sindiri, Sivasish, Patidar, Rajesh, Higham, Christine S, Dombi, Eva, Miettinen, Markku M, Fetsch, Patricia, Brems, Hilde, Chandrasekharappa, Settara C, Jones, Kristine, Zhu, Bin, Wei, Jun S, Mullikin, James C, Wallace, Margaret R, Khan, Javed, Legius, Eric, Widemann, Brigitte C, Stewart, Douglas R
Publicado no Neuro Oncol (2019)

Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion

Por Heitzeneder, Sabine, Sotillo, Elena, Shern, Jack F, Sindiri, Sivasish, Xu, Peng, Jones, Robert, Pollak, Michael, Noer, Pernille R, Lorette, Julie, Fazli, Ladan, Alag, Anya, Meltzer, Paul, Lau, Ching, Conover, Cheryl A, Oxvig, Claus, Sorensen, Poul H, Maris, John M, Khan, Javed, Mackall, Crystal L
Publicado no J Natl Cancer Inst (2019)

Outcome-related signatures identified by Whole Transcriptome Sequencing of Resectable Stage III/IV Melanoma Evaluated After Starting Hu14.18-IL2

Por Yang, Richard K., Kuznetsov, Igor B., Ranheim, Erik A., Wei, Jun S., Sindiri, Sivasish, Gryder, Berkley, Gangalapudi, Vineela, Song, Young K., Patel, Viharkumar, Hank, Jacquelyn A., Zuleger, Cindy, Erbe, Amy K., Morris, Zachary S., Quale, Renae, Kim, KyungMann, Albertini, Mark R., Khan, Javed, Sondel, Paul M.
Publicado no Clin Cancer Res (2020)

APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors

Por Nitin Roper, Shaojian Gao, Tapan K. Maity, A. Rouf Banday, Xu Zhang, Abhilash Venugopalan, Constance M. Cultraro, Rajesh Patidar, Sivasish Sindiri, Anna-Leigh Brown, Alexander Goncearenco, Anna R. Panchenko, Romi Biswas, Anish Thomas, Arun Rajan, Corey A. Carter, David E. Kleiner, Stephen M. Hewitt, Javed Khan, Ludmila Prokunina-Olsson, Udayan Guha
Publicado em 2019-03-01

APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors

Por Roper, Nitin, Gao, Shaojian, Maity, Tapan K., Banday, A. Rouf, Zhang, Xu, Venugopalan, Abhilash, Cultraro, Constance M., Patidar, Rajesh, Sindiri, Sivasish, Brown, Anna-Leigh, Goncearenco, Alexander, Panchenko, Anna R., Biswas, Romi, Thomas, Anish, Rajan, Arun, Carter, Corey A., Kleiner, David E., Hewitt, Stephen M., Khan, Javed, Prokunina-Olsson, Ludmila, Guha, Udayan
Publicado no Cell Rep (2019)

The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma

Por Ignatius, Myron S., Hayes, Madeline N., Lobbardi, Riadh, Chen, Eleanor Y., McCarthy, Karin M., Sreenivas, Prethish, Motala, Zainab, Durbin, Adam D., Molodtsov, Aleksey, Reeder, Sophia, Jin, Alexander, Sindiri, Sivasish, Beleyea, Brian C., Bhere, Deepak, Alexander, Matthew S., Shah, Khalid, Keller, Charles, Linardic, Corinne M., Nielsen, Petur G., Malkin, David, Khan, Javed, Langenau, David M.
Publicado no Cell Rep (2017)

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors

Por Shern, Jack F., Chen, Li, Chmielecki, Juliann, Wei, Jun S., Patidar, Rajesh, Rosenberg, Mara, Ambrogio, Lauren, Auclair, Daniel, Wang, Jianjun, Song, Young K., Tolman, Catherine, Hurd, Laura, Liao, Hongling, Zhang, Shile, Bogen, Dominik, Brohl, Andrew S., Sindiri, Sivasish, Catchpoole, Daniel, Badgett, Thomas, Getz, Gad, Mora, Jaume, Anderson, James R., Skapek, Stephen X., Barr, Frederic G., Meyerson, Matthew, Hawkins, Douglas S., Khan, Javed
Publicado no Cancer Discov (2014)

Multi-Dimensional Omics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: Report from Pediatric Oncology Branch, NCI

Por Chang, Wendy, Brohl, Andrew S., Patidar, Rajesh, Sindiri, Sivasish, Shern, Jack F., Wei, Jun S., Song, Young K., Yohe, Marielle E., Gryder, Berkley, Zhang, Shile, Calzone, Kathleen A., Shivaprasad, Nityashree, Wen, Xinyu, Badgett, Thomas C., Miettinen, Markku, Hartman, Kip R., League-Pascual, James C., Trahair, Toby N., Widemann, Brigitte C., Merchant, Melinda S., Kaplan, Rosandra N., Lin, Jimmy C., Khan, Javed
Publicado no Clin Cancer Res (2016)

The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation

Por Brohl, Andrew S., Solomon, David A., Chang, Wendy, Wang, Jianjun, Song, Young, Sindiri, Sivasish, Patidar, Rajesh, Hurd, Laura, Chen, Li, Shern, Jack F., Liao, Hongling, Wen, Xinyu, Gerard, Julia, Kim, Jung-Sik, Lopez Guerrero, Jose Antonio, Machado, Isidro, Wai, Daniel H., Picci, Piero, Triche, Timothy, Horvai, Andrew E., Miettinen, Markku, Wei, Jun S., Catchpool, Daniel, Llombart-Bosch, Antonio, Waldman, Todd, Khan, Javed
Publicado em 2014

Recurrent inactivating RASA2 mutations in melanoma

Por Arafeh, Rand, Qutob, Nouar, Emmanuel, Rafi, Keren-Paz, Alona, Madore, Jason, Elkahloun, Abdel, Wilmott, James S., Gartner, Jared J., Di Pizio, Antonella, Winograd-Katz, Sabina, Sindiri, Sivasish, Rotkopf, Ron, Dutton-Regester, Ken, Johansson, Peter, Pritchard, Antonia, Waddell, Nicola, Hill, Victoria K., Lin, Jimmy C., Hevroni, Yael, Rosenberg, Steven A., Khan, Javed, Ben-Dor, Shifra, Niv, Masha Y., Ulitsky, Igor, Mann, Graham J, Scolyer, Richard A., Hayward, Nicholas K., Samuels, Yardena
Publicado no Nat Genet (2015)

Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer

Por Roper, Nitin, Brown, Anna-Leigh, Wei, Jun S., Pack, Svetlana, Trindade, Christopher, Kim, Chul, Restifo, Olivia, Gao, Shaojian, Sindiri, Sivasish, Mehrabadi, Farid, El Meskini, Rajaa, Ohler, Zoe Weaver, Maity, Tapan K., Venugopalan, Abhilash, Cultraro, Constance M., Akoth, Elizabeth, Padiernos, Emerson, Chen, Haobin, Kesarwala, Aparna, Smart, DeeDee K., Nilubol, Naris, Rajan, Arun, Piotrowska, Zofia, Xi, Liqiang, Raffeld, Mark, Panchenko, Anna R., Sahinalp, Cenk, Hewitt, Stephen, Hoang, Chuong D., Khan, Javed, Guha, Udayan
Publicado no Cell Rep Med (2020)

Insights into pediatric rhabdomyosarcoma research: challenges and goals

Por Yohe, Marielle E., Heske, Christine M., Stewart, Elizabeth, Adamson, Peter C., Ahmed, Nabil, Antonescu, Cristina R., Chen, Eleanor, Collins, Natalie, Ehrlich, Alan, Galindo, Rene L., Gryder, Berkley E., Hahn, Heidi, Hammond, Sharon, Hatley, Mark E., Hawkins, Douglas S., Hayes, Madeline N., Hayes-Jordan, Andrea, Helman, Lee J., Hettmer, Simone, Ignatius, Myron S., Keller, Charles, Khan, Javed, Kirsch, David G., Linardic, Corinne M., Lupo, Philip J., Rota, Rossella, Shern, Jack F., Shipley, Janet, Sindiri, Sivasish, Tapscott, Stephen J., Vakoc, Christopher R., Wexler, Leonard H., Langenau, David M.
Publicado no Pediatr Blood Cancer (2019)