The development of antibody –based immunotherapy with (EMD-273063) Hu14.18-IL2 in melanoma and neuroblastoma

by Yamane, Brett H., Hank, Jacquelyn A., Albertini, Mark R., Sondel, Paul M.
Published 2009

NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity in Cancer Immunotherapy

by Wang, Wei, Erbe, Amy K., Hank, Jacquelyn A., Morris, Zachary S., Sondel, Paul M.
Published in Front Immunol (2015)

Genotyping Single Nucleotide Polymorphisms (SNPs) and Copy Number Variability (CNV) of the FCGRs (FCGR3A and FCGR2C) expressed on NK cells

by Erbe, Amy K., Wang, Wei, Gallenberger, Mikayla, Hank, Jacquelyn A., Sondel, Paul M.
Published in Methods Mol Biol (2016)

Rhamnose Glycoconjugates for the Recruitment of Endogenous Anti-carbohydrate Antibodies to Tumor Cells

by Sheridan, Rachael T. C., Hudon, Jonathan, Hank, Jacquelyn A., Sondel, Paul M., Kiessling, Laura L.
Published 2014

NK Cell-based Immunotherapies in Pediatric Oncology

by McDowell, Kimberly A., Hank, Jacquelyn A., DeSantes, Kenneth B., Capitini, Christian M., Otto, Mario, Sondel, Paul M.
Published in J Pediatr Hematol Oncol (2015)

Human and murine IL2 receptors differentially respond to the human-IL2 component of immunocytokines

by Perez Horta, Zulmarie, Saseedhar, Swetha, Rakhmilevich, Alexander L., Carmichael, Lakeesha, Hank, Jacquelyn A., Boyden, Margaret, Gillies, Stephen D., Sondel, Paul M.
Published in Oncoimmunology (2018)

Human NK cells maintain licensing status and are subject to killer immunoglobulin-like receptor (KIR) and KIR-ligand inhibition following ex vivo expansion

by Wang, Wei, Erbe, Amy K., Alderson, Kory A., Phillips, Emily, Gallenberger, Mikayla, Gan, Jacek, Campana, Dario, Hank, Jacquelyn A., Sondel, Paul M.
Published in Cancer Immunol Immunother (2016)

A Phase 1 and pharmacokinetic study evaluating daily or weekly schedules of the humanized anti-GD2 antibody hu14.18K322A in recurrent/refractory solid tumors

by Bishop, Michael W., Hutson, Paul R., Hank, Jacquelyn A., Sondel, Paul M., Furman, Wayne L., Meagher, Michael M., Navid, Fariba, Santana, Victor M.
Published in MAbs (2020)

Increasing the Clinical Efficacy of NK and Antibody-Mediated Cancer Immunotherapy: Potential Predictors of Successful Clinical Outcome Based on Observations in High-Risk Neuroblast...

by Koehn, Tony A., Trimble, Lori L., Alderson, Kory L., Erbe, Amy K., McDowell, Kimberly A., Grzywacz, Bartosz, Hank, Jacquelyn A., Sondel, Paul M.
Published 2012

Immunogenicity of the Hu14.18-IL2 Immunocytokine Molecule in Adults with Melanoma and Children with Neuroblastoma

by Hank, Jacquelyn A., Gan, Jacek, Ryu, Hyunji, Ostendorf, Amy, Stauder, Michael C., Sternberg, Adam, Albertini, Mark, Lo, Kin-Ming, Gillies, Stephen D., Eickhoff, Jens, Sondel, Paul M.
Published 2009

Phase II trial of hu14.18-IL2 for patients with metastatic melanoma

by Albertini, Mark R., Hank, Jacquelyn A., Gadbaw, Brian, Kostlevy, Jordan, Haldeman, Jennifer, Schalch, Heidi, Gan, Jacek, Kim, KyungMann, Eickhoff, Jens, Gillies, Stephen D., Sondel, Paul M.
Published 2012

Phase I Study of ch14.18 With Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-2 in Children With Neuroblastoma After Autologous Bone Marrow Transplantation or Stem...

by Gilman, Andrew L., Ozkaynak, M. Fevzi, Matthay, Katherine K., Krailo, Mark, Yu, Alice L., Gan, Jacek, Sternberg, Adam, Hank, Jacquelyn A., Seeger, Robert, Reaman, Gregory H., Sondel, Paul M.
Published 2009

Ab-IL2 fusion proteins mediate NK cell immune synapse formation by polarizing CD25 to the target cell-effector cell interface

by Gubbels, Jennifer A. A., Gadbaw, Brian, Buhtoiarov, Ilia N., Horibata, Sachi, Kapur, Arvinder K., Patel, Dhara, Hank, Jacquelyn A., Gillies, Stephen D., Sondel, Paul M., Patankar, Manish S., Connor, Joseph
Published 2011

Anti-tumor and immunomodulatory activity of resveratrol in vitro and its potential for combining with cancer immunotherapy

by Soto, Brenda L., Hank, Jacquelyn A., Darjatmoko, Soesiawati R., Polans, Arthur S., Yanke, Eric M., Rakhmilevich, Alexander L., Seo, Songwon, Kim, KyungMann, Reisfeld, Ralph A., Gillies, Stephen D., Sondel, Paul M.
Published 2011

Depth of tumor implantation affects response to in situ vaccination in a syngeneic murine melanoma model

by Carlson, Peter M, Mohan, Manasi, Rodriguez, Matthew, Subbotin, Vladimir, Sun, Claire X, Patel, Ravi B, Birstler, Jen, Hank, Jacquelyn A, Rakhmilevich, Alexander L, Morris, Zachary S, Erbe, Amy K, Sondel, Paul M
Published in J Immunother Cancer (2021)

Intratumoral injection reduces toxicity and antibody-mediated neutralization of immunocytokine in a mouse melanoma model

by Baniel, Claire C, Sumiec, Elizabeth G, Hank, Jacquelyn A, Bates, Amber M, Erbe, Amy K, Pieper, Alexander A, Hoefges, Anna G, Patel, Ravi B, Rakhmilevich, Alexander L, Morris, Zachary S, Sondel, Paul M
Published in J Immunother Cancer (2020)

Intratumoral Immunocytokine Treatment Results in Enhanced Antitumor Effects

by Johnson, Erik E., Lum, Hillary D., Rakhmilevich, Alexander L., Schmidt, Brian E., Furlong, Meghan, Buhtoiarov, Ilia N., Hank, Jacquelyn A., Raubitschek, Andrew, Colcher, David, Reisfeld, Ralph A., Gillies, Stephen D., Sondel, Paul M.
Published 2008

Differential internalization of hu14.18-IL2 immunocytokine by NK and tumor cell: impact on conjugation, cytotoxicity, and targeting

by Buhtoiarov, Ilia N., Neal, Zane C., Gan, Jacek, Buhtoiarova, Tatiana N., Patankar, Manish S., Gubbels, Jennifer A. A., Hank, Jacquelyn A., Yamane, Brett, Rakhmilevich, Alexander L., Reisfeld, Ralph A., Gillies, Stephen D., Sondel, Paul M.
Published 2011

Intratumoral hu14.18–IL-2 (IC) Induces Local and Systemic Antitumor Effects That Involve Both Activated T and NK Cells As Well As Enhanced IC Retention

by Yang, Richard K., Kalogriopoulos, Nicholas A., Rakhmilevich, Alexander L., Ranheim, Erik A., Seo, Songwon, Kim, KyungMann, Alderson, Kory L., Gan, Jacek, Reisfeld, Ralph A., Gillies, Stephen D., Hank, Jacquelyn A., Sondel, Paul M.
Published 2012

Intratumoral treatment of smaller mouse neuroblastoma tumors with a recombinant protein consisting of IL-2 linked to the Hu14.18 antibody increases intratumoral CD8+ T and NK cells...

by Yang, Richard K., Kalogriopoulos, Nicholas A., Rakhmilevich, Alexander L., Ranheim, Erik A., Seo, Songwon, Kim, KyungMann, Alderson, Kory L., Gan, Jacek, Reisfeld, Ralph A., Gillies, Stephen D., Hank, Jacquelyn A., Sondel, Paul M.
Published 2013