The role of PAPP-A in the IGF system: location, location, location

Por Oxvig, Claus
Publicado no J Cell Commun Signal (2015)

Experimental support for a β-propeller domain in integrin α-subunits and a calcium binding site on its lower surface

Por Oxvig, Claus, Springer, Timothy A.
Publicado em 1998

PAPP‐A: a promising therapeutic target for healthy longevity

Por Conover, Cheryl A., Oxvig, Claus
Publicado no Aging Cell (2016)

Conformational changes in tertiary structure near the ligand binding site of an integrin I domain

Por Oxvig, Claus, Lu, Chafen, Springer, Timothy A.
Publicado em 1999

An isolated, surface-expressed I domain of the integrin αLβ2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond

Por Lu, Chafen, Shimaoka, Motomu, Ferzly, Mazen, Oxvig, Claus, Takagi, Junichi, Springer, Timothy A.
Publicado em 2001

α(3)Na(+)/K(+)-ATPase Deficiency Causes Brain Ventricle Dilation and Abrupt Embryonic Motility in Zebrafish

Por Doğanlı, Canan, Beck, Hans C., Ribera, Angeles B., Oxvig, Claus, Lykke-Hartmann, Karin
Publicado em 2013

A Novel Neutralizing Antibody Targeting Pregnancy-Associated Plasma Protein-A Inhibits Ovarian Cancer Growth and Ascites Accumulation in Patient Mouse Tumorgrafts

Por Becker, Marc A., Haluska, Paul, Bale, Laurie K., Oxvig, Claus, Conover, Cheryl A.
Publicado no Mol Cancer Ther (2015)

Effects of Mutated Pregnancy-Associated Plasma Protein-A on Atherosclerotic Lesion Development in Mice

Por Boldt, Henning B., Bale, Laurie K., Resch, Zachary T., Oxvig, Claus, Overgaard, Michael T., Conover, Cheryl A.
Publicado em 2013

Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity

Por Mikkelsen, Jakob H., Resch, Zachary T., Kalra, Bhanu, Savjani, Gopal, Kumar, Ajay, Conover, Cheryl A., Oxvig, Claus
Publicado em 2014

Duplication and Diversification of the Hypoxia-Inducible IGFBP-1 Gene in Zebrafish

Por Kamei, Hiroyasu, Lu, Ling, Jiao, Shuang, Li, Yun, Gyrup, Claus, Laursen, Lisbeth S., Oxvig, Claus, Zhou, Jianfeng, Duan, Cunming
Publicado em 2008

Transgenic overexpression of pregnancy-associated plasma protein-A in murine arterial smooth muscle accelerates atherosclerotic lesion development

Por Conover, Cheryl A., Mason, Megan A., Bale, Laurie K., Harrington, Sean C., Nyegaard, Mette, Oxvig, Claus, Overgaard, Michael T.
Publicado em 2010

Porcine synapsin 1: SYN1 gene analysis and functional characterization of the promoter()()

Por Hedegaard, Claus, Kjaer-Sorensen, Kasper, Madsen, Lone Bruhn, Henriksen, Carina, Momeni, Jamal, Bendixen, Christian, Oxvig, Claus, Larsen, Knud
Publicado em 2013

Pregnancy-Associated Plasma Protein-A Expression in Human Breast Cancer

Por Mansfield, Aaron S., Visscher, Daniel W., Hart, Steven N., Wang, Chen, Goetz, Matthew P., Oxvig, Claus, Conover, Cheryl A.
Publicado no Growth Horm IGF Res (2014)

Stanniocalcin-2 Inhibits Mammalian Growth by Proteolytic Inhibition of the Insulin-like Growth Factor Axis

Por Jepsen, Malene R., Kløverpris, Søren, Mikkelsen, Jakob H., Pedersen, Josefine H., Füchtbauer, Ernst-Martin, Laursen, Lisbeth S., Oxvig, Claus
Publicado no J Biol Chem (2015)

Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A

Por Kløverpris, Søren, Mikkelsen, Jakob H., Pedersen, Josefine H., Jepsen, Malene R., Laursen, Lisbeth S., Petersen, Steen V., Oxvig, Claus
Publicado no J Biol Chem (2015)

Mice Deficient in PAPP-A Show Resistance to the Development of Diabetic Nephropathy

Por Mader, Jessica R., Resch, Zachary T., McLean, Gary R., Mikkelsen, Jakob H., Oxvig, Claus, Marler, Ronald J., Conover, Cheryl A.
Publicado em 2013

Molecular Cloning and Characterization of Porcine Na(+)/K(+)-ATPase Isoforms α1, α2, α3 and the ATP1A3 Promoter

Por Henriksen, Carina, Kjaer-Sorensen, Kasper, Einholm, Anja Pernille, Madsen, Lone Bruhn, Momeni, Jamal, Bendixen, Christian, Oxvig, Claus, Vilsen, Bente, Larsen, Knud
Publicado em 2013

Identification of Transglutaminase Reactive Residues in Human Osteopontin and Their Role in Polymerization

Por Christensen, Brian, Zachariae, Elias D., Scavenius, Carsten, Thybo, Morten, Callesen, Morten M., Kløverpris, Søren, Oxvig, Claus, Enghild, Jan J., Sørensen, Esben S.
Publicado no PLoS One (2014)

The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A

Por Lawrence, James B., Oxvig, Claus, Overgaard, Michael T., Sottrup-Jensen, Lars, Gleich, Gerald J., Hays, Lara G., Yates, John R., Conover, Cheryl A.
Publicado em 1999

Lactation opposes pappalysin‐1‐driven pregnancy‐associated breast cancer

Por Takabatake, Yukie, Oxvig, Claus, Nagi, Chandandeep, Adelson, Kerin, Jaffer, Shabnam, Schmidt, Hank, Keely, Patricia J, Eliceiri, Kevin W, Mandeli, John, Germain, Doris
Publicado no EMBO Mol Med (2016)