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PAPP‐A: a promising therapeutic target for healthy longevity
Pregnancy‐associated plasma protein‐A (PAPP‐A) is a proteolytic enzyme that was discovered to increase local insulin‐like growth factor (IGF) availability for receptor activation through cleavage of inhibitory IGF binding proteins (IGFBPs). Reduced IGF signaling has been associated with increased li...
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| Publicado no: | Aging Cell |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5334524/ https://ncbi.nlm.nih.gov/pubmed/28035757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12564 |
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