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PAPP-A and the IGF system in atherosclerosis: what’s up, what’s down?
Pregnancy-associated plasma protein-A (PAPP-A) is a metalloproteinase with a well-established role in releasing bioactive insulin-like growth factor-1 (IGF-1) from IGF-binding protein-2, -4, and -5 by proteolytic processing of these. The IGF system has repeatedly been suggested to be involved in the...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6879922/ https://ncbi.nlm.nih.gov/pubmed/31518159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00395.2019 |
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