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PAPP-A and the IGF system in atherosclerosis: what’s up, what’s down?

Pregnancy-associated plasma protein-A (PAPP-A) is a metalloproteinase with a well-established role in releasing bioactive insulin-like growth factor-1 (IGF-1) from IGF-binding protein-2, -4, and -5 by proteolytic processing of these. The IGF system has repeatedly been suggested to be involved in the...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Steffensen, Lasse B., Conover, Cheryl A., Oxvig, Claus
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879922/
https://ncbi.nlm.nih.gov/pubmed/31518159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00395.2019
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