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Mice Deficient in PAPP-A Show Resistance to the Development of Diabetic Nephropathy

We investigated pregnancy-associated plasma protein-A (PAPP-A) in diabetic nephropathy. Normal human kidney showed specific staining for PAPP-A in glomeruli, and this staining was markedly increased in diabetic kidney. To assess possible contribution of PAPP-A in the development of diabetic nephropa...

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Bibliografske podrobnosti
Main Authors: Mader, Jessica R., Resch, Zachary T., McLean, Gary R., Mikkelsen, Jakob H., Oxvig, Claus, Marler, Ronald J., Conover, Cheryl A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820014/
https://ncbi.nlm.nih.gov/pubmed/23881937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-13-0167
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