Melanoma Brain Metastasis: Mechanisms, Models, and Medicine

di Kircher, David A., Silvis, Mark R., Cho, Joseph H., Holmen, Sheri L.
Pubblicato in Int J Mol Sci (2016)

αE-catenin inhibits a Src–YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway

di Li, Peng, Silvis, Mark R., Honaker, Yuchi, Lien, Wen-Hui, Arron, Sarah T., Vasioukhin, Valeri
Pubblicato in Genes Dev (2016)

Rab11b Regulates the Apical Recycling of the Cystic Fibrosis Transmembrane Conductance Regulator in Polarized Intestinal Epithelial Cells

di Silvis, Mark R., Bertrand, Carol A., Ameen, Nadia, Golin-Bisello, Franca, Butterworth, Michael B., Frizzell, Raymond A., Bradbury, Neil A.
Pubblicazione 2009

Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC)

di Butterworth, Michael B., Edinger, Robert S., Silvis, Mark R., Gallo, Luciana I., Liang, Xiubin, Apodaca, Gerard, Fizzell, Raymond A., Johnson, John P.
Pubblicazione 2012

α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1

di Silvis, Mark R., Kreger, Bridget T., Lien, Wen-Hui, Klezovitch, Olga, Rudakova, G. Marianna, Camargo, Fernando D., Lantz, Dan M., Seykora, John T., Vasioukhin, Valeri
Pubblicazione 2011

ERG activates the YAP1 transcriptional program and induces the development of age-related prostate tumors

di Nguyen, Liem T., Tretiakova, Maria S., Silvis, Mark R., Lucas, Jared, Klezovitch, Olga, Coleman, Ilsa, Bolouri, Hamid, Kutyavin, Vassily I., Morrissey, Colm, True, Lawrence D., Nelson, Peter S., Vasioukhin, Valeri
Pubblicato in Cancer Cell (2015)

Resistance mechanisms to genetic suppression of mutant NRAS in melanoma

di Robinson, James P., Rebecca, Vito W., Kircher, David A., Silvis, Mark R., Smalley, Inna, Gibney, Geoffrey T., Lastwika, Kristin J., Chen, Guo, Davies, Michael A., Grossman, Douglas, Smalley, Keiran S.M., Holmen, Sheri L., VanBrocklin, Matthew W.
Pubblicato in Melanoma Res (2017)

Mutant IDH1 Promotes Glioma Formation In Vivo

di Philip, Beatrice, Yu, Diana X., Silvis, Mark R., Shin, Clifford H., Robinson, James P., Robinson, Gemma L., Welker, Adam E., Angel, Stephanie N., Tripp, Sheryl R., Sonnen, Joshua A., VanBrocklin, Matthew W., Gibbons, Richard J., Looper, Ryan E., Colman, Howard, Holmen, Sheri L.
Pubblicato in Cell Rep (2018)

A Nonsynonymous Variant in the GOLM1 Gene in Cutaneous Malignant Melanoma

di Teerlink, Craig C, Huff, Chad, Stevens, Jeff, Yu, Yao, Holmen, Sheri L, Silvis, Mark R, Trombetti, Kirby, Zhao, Hua, Grossman, Douglas, Farnham, James M, Wen, Jingran, Facelli, Julio C, Thomas, Alun, Babst, Markus, Florell, Scott R, Meyer, Laurence, Zone, John J, Leachman, Sancy, Cannon-Albright, Lisa A
Pubblicato in J Natl Cancer Inst (2018)

AKT1(E17K) activates focal adhesion kinase and promotes melanoma brain metastasis

di Kircher, David A., Trombetti, Kirby A., Silvis, Mark R., Parkman, Gennie L., Fischer, Grant M., Angel, Stephanie N., Stehn, Christopher M., Strain, Sean C., Grossmann, Allie H., Duffy, Keith L., Boucher, Kenneth M., McMahon, Martin, Davies, Michael A., Mendoza, Michelle C., VanBrocklin, Matthew W., Holmen, Sheri L.
Pubblicato in Mol Cancer Res (2019)

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma

di Yu, Yong, Schleich, Kolja, Yue, Bin, Ji, Sujuan, Lohneis, Philipp, Kemper, Kristel, Silvis, Mark R., Qutob, Nouar, van Rooijen, Ellen, Werner-Klein, Melanie, Li, Lianjie, Dhawan, Dhriti, Meierjohann, Svenja, Reimann, Maurice, Elkahloun, Abdel, Treitschke, Steffi, Dörken, Bernd, Speck, Christian, Mallette, Frédérick A., Zon, Leonard I., Holmen, Sheri L., Peeper, Daniel S., Samuels, Yardena, Schmitt, Clemens A., Lee, Soyoung
Pubblicato in Cancer Cell (2018)