Intracellular Processing of α(1)-Antitrypsin

Por Sifers, Richard N.
Publicado em 2010

Resurrecting the Protein Fold for Disease Intervention

Por Sifers, Richard N.
Publicado em 2013

Golgi-situated endoplasmic reticulum α-1, 2-mannosidase contributes to the retrieval of ERAD substrates through a direct interaction with γ-COP

Por Pan, Shujuan, Cheng, Xiaoyun, Sifers, Richard N.
Publicado em 2013

The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I

Por Termine, Daniel J., Moremen, Kelley W., Sifers, Richard N.
Publicado em 2009

Elucidation of the molecular logic by which misfolded α1-antitrypsin is preferentially selected for degradation

Por Wu, Ying, Swulius, Matthew T., Moremen, Kelley W., Sifers, Richard N.
Publicado em 2003

Organizational Diversity among Distinct Glycoprotein Endoplasmic Reticulum-associated Degradation Programs

Por Cabral, Christopher M., Liu, Yan, Moremen, Kelley W., Sifers, Richard N.
Publicado em 2002

A Golgi-localized Mannosidase (MAN1B1) Plays a Non-enzymatic Gatekeeper Role in Protein Biosynthetic Quality Control

Por Iannotti, Michael J., Figard, Lauren, Sokac, Anna M., Sifers, Richard N.
Publicado em 2014

Human Endoplasmic Reticulum Mannosidase I Is Subject to Regulated Proteolysis

Por Wu, Ying, Termine, Daniel J., Swulius, Matthew T., Moremen, Kelley W., Sifers, Richard N.
Publicado em 2006

SNP-mediated translational suppression of ERManI modifies the onset of end-stage liver disease in alpha1-antitrypsin deficiency

Por Pan, Shujuan, Huang, Lu, McPherson, John, Muzny, Donna, Rouhani, Farshid, Brantly, Mark, Gibbs, Richard, Sifers, Richard N.
Publicado em 2009

β-N-Acetylglucosamine (O-GlcNAc) Is a Novel Regulator of Mitosis-specific Phosphorylations on Histone H3

Por Fong, Jerry J., Nguyen, Brenda L., Bridger, Robert, Medrano, Estela E., Wells, Lance, Pan, Shujuan, Sifers, Richard N.
Publicado em 2012

Golgi localization of ERManI defines spatial separation of the mammalian glycoprotein quality control system

Por Pan, Shujuan, Wang, Shufang, Utama, Budi, Huang, Lu, Blok, Neil, Estes, Mary K., Moremen, Kelley W., Sifers, Richard N.
Publicado em 2011

ERManI Is a Target of miR-125b and Promotes Transformation Phenotypes in Hepatocellular Carcinoma (HCC)

Por Pan, Shujuan, Cheng, Xiaoyun, Chen, Hongan, Castro, Patricia D., Ittmann, Michael M., Hutson, Anne W., Zapata, Susan K., Sifers, Richard N.
Publicado em 2013

Correction: ERManI Is a Target of miR-125b and Promotes Transformation Phenotypes in Hepatocellular Carcinoma (HCC)

Por Pan, Shujuan, Cheng, Xiaoyun, Chen, Hongan, Castro, Patricia D., Ittmann, Michael M., Hutson, Anne W., Zapata, Susan K., Sifers, Richard N.
Publicado em 2014

γ-Glutamyl Leukotrienase, a Novel Endothelial Membrane Protein, Is Specifically Responsible for Leukotriene D(4) Formation in Vivo

Por Han, Bing, Luo, Guoyang, Shi, Zheng-Zheng, Barrios, Roberto, Atwood, Donna, Liu, Weili, Habib, Geetha M., Sifers, Richard N., Corry, David B., Lieberman, Michael W.
Publicado em 2002

Small molecules block the polymerisation of Z α(1)-antitrypsin and increase the clearance of intracellular aggregates

Por Mallya, Meera, Phillips, Russell L., Saldanha, S. Adrian, Gooptu, Bibek, Leigh Brown, Sarah C., Termine, Daniel J., Shirvani, Arash M., Wu, Ying, Sifers, Richard N., Abagyan, Ruben, Lomas, David A
Publicado em 2007

Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution

Por Mamrosh, Jennifer L, Lee, Jae Man, Wagner, Martin, Stambrook, Peter J, Whitby, Richard J, Sifers, Richard N, Wu, San-Pin, Tsai, Ming-Jer, DeMayo, Francesco J, Moore, David D
Publicado em 2014

Correction: Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution

Por Mamrosh, Jennifer L, Lee, Jae Man, Wagner, Martin, Stambrook, Peter J, Whitby, Richard J, Sifers, Richard N, Wu, San-Pin, Tsai, Ming-Jer, DeMayo, Francesco J, Moore, David D
Publicado no eLife (2015)