ERManI Is a Target of miR-125b and Promotes Transformation Phenotypes in Hepatocellular Carcinoma (HCC)

The MAN1B1 gene product, designated ER alpha-1, 2-mannosidase (ERManI), is an enzyme localized in the Golgi complex of mammalian cells. By functioning as a “gate keeper” to prevent the inappropriate secretion of misfolded glycoproteins, it plays a critical role in maintaining protein homeostasis in...

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Autors principals: Pan, Shujuan, Cheng, Xiaoyun, Chen, Hongan, Castro, Patricia D., Ittmann, Michael M., Hutson, Anne W., Zapata, Susan K., Sifers, Richard N.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733964/
https://ncbi.nlm.nih.gov/pubmed/23940818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072829
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