The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I

The secretory pathway provides a physical route through which only correctly folded gene products are delivered to the eukaryotic cell surface. The efficiency of endoplasmic reticulum (ER)-associated degradation (ERAD), which orchestrates the clearance of structurally aberrant proteins under basal c...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Termine, Daniel J., Moremen, Kelley W., Sifers, Richard N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Company of Biologists 2009
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720930/
https://ncbi.nlm.nih.gov/pubmed/19258393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.037291
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