Intracellular Processing of α(1)-Antitrypsin

α(1)-Antitrypsin (AAT) secreted from hepatocytes is an inhibitor of neutrophil elastase. Its normal circulating concentration functions to maintain the elasticity of the lung by preventing the hydrolytic destruction of elastin fibers. Severely diminished circulating concentrations of AAT, resulting...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Sifers, Richard N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2010
Pynciau:
Twenty-Fifth Transatlantic Airway Conference: Protein Misfolding and Obstructive Lung Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136957/
https://ncbi.nlm.nih.gov/pubmed/21030516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.201001-011AW
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