Intracellular Processing of α(1)-Antitrypsin

α(1)-Antitrypsin (AAT) secreted from hepatocytes is an inhibitor of neutrophil elastase. Its normal circulating concentration functions to maintain the elasticity of the lung by preventing the hydrolytic destruction of elastin fibers. Severely diminished circulating concentrations of AAT, resulting...

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Bibliographische Detailangaben
1. Verfasser: Sifers, Richard N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2010
Schlagworte:
Twenty-Fifth Transatlantic Airway Conference: Protein Misfolding and Obstructive Lung Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136957/
https://ncbi.nlm.nih.gov/pubmed/21030516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.201001-011AW
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