The Unfolded Protein Response in Lung Disease

The early steps in the biogenesis of secreted and membrane proteins occur in the lumen of the endoplasmic reticulum (ER), where resident proteins that make up the ER machinery assist in their folding, maturation, and complex assembly. Variation in the load of ER client proteins and in the function o...

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Autores principales: Marcinak, Stefan J., Ron, David
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2010
Materias:
Twenty-Fifth Transatlantic Airway Conference: Protein Misfolding and Obstructive Lung Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136955/
https://ncbi.nlm.nih.gov/pubmed/21030513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.201001-015AW
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