Lung Disease Associated with α(1)-Antitrypsin Deficiency

α(1)-Antitrypsin (A1AT) is a polyvalent, acute-phase reactant with an extensive range of biological functions that go beyond those usually linked to its antiprotease (serpin) activities. Genetic mutations cause a systemic deficiency of A1AT, leading to liver and pulmonary diseases, including emphyse...

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Detalhes bibliográficos
Main Authors: Tuder, Rubin M., Janciauskiene, Sabina M., Petrache, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
Twenty-Fifth Transatlantic Airway Conference: Protein Misfolding and Obstructive Lung Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136958/
https://ncbi.nlm.nih.gov/pubmed/21030517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.201002-020AW
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