Intracellular Processing of α(1)-Antitrypsin

α(1)-Antitrypsin (AAT) secreted from hepatocytes is an inhibitor of neutrophil elastase. Its normal circulating concentration functions to maintain the elasticity of the lung by preventing the hydrolytic destruction of elastin fibers. Severely diminished circulating concentrations of AAT, resulting...

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Hlavní autor: Sifers, Richard N.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2010
Témata:
Twenty-Fifth Transatlantic Airway Conference: Protein Misfolding and Obstructive Lung Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136957/
https://ncbi.nlm.nih.gov/pubmed/21030516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.201001-011AW
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