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Golgi-situated endoplasmic reticulum α-1, 2-mannosidase contributes to the retrieval of ERAD substrates through a direct interaction with γ-COP

Endoplasmic reticulum (ER) α-1, 2-mannosidase (ERManI) contributes to ER-associated protein degradation (ERAD) by initiating the formation of degradation signals on misfolded N-linked glycoproteins. Despite its inferred intracellular location, we recently discovered that the mammalian homologue is a...

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Detalhes bibliográficos
Main Authors: Pan, Shujuan, Cheng, Xiaoyun, Sifers, Richard N.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623633/
https://ncbi.nlm.nih.gov/pubmed/23427261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-12-0886
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