Effect of asymmetric terminal structures of short RNA duplexes on the RNA interference activity and strand selection

por Sano, Masayuki, Sierant, Malgorzata, Miyagishi, Makoto, Nakanishi, Mahito, Takagi, Yasuomi, Sutou, Shizuyo
Publicado 2008

Evaluation of BACE1 Silencing in Cellular Models

por Sierant, Malgorzata, Kubiak, Katarzyna, Kazmierczak-Baranska, Julia, Warashina, Masaki, Kuwabara, Tomoko, Nawrot, Barbara
Publicado 2009

S-Geranyl-2-thiouridine wobble nucleosides of bacterial tRNAs; chemical and enzymatic synthesis of S-geranylated-RNAs and their physicochemical characterization

por Sierant, Malgorzata, Leszczynska, Grazyna, Sadowska, Klaudia, Dziergowska, Agnieszka, Rozanski, Michal, Sochacka, Elzbieta, Nawrot, Barbara
Publicado en Nucleic Acids Res (2016)

Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference

por Sierant, Malgorzata, Paduszynska, Alina, Kazmierczak-Baranska, Julia, Nacmias, Benedetta, Sorbi, Sandro, Bagnoli, Silvia, Sochacka, Elzbieta, Nawrot, Barbara
Publicado 2011

Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity

por Dolot, Rafal, Lam, Curtis H, Sierant, Malgorzata, Zhao, Qiang, Liu, Feng-Wu, Nawrot, Barbara, Egli, Martin, Yang, Xianbin
Publicado en Nucleic Acids Res (2018)

Gene Silencing Activity of siRNA Molecules Containing Phosphorodithioate Substitutions

por Yang, Xianbin, Sierant, Malgorzata, Janicka, Magdalena, Peczek, Lukasz, Martinez, Carlos, Hassell, Tom, Li, Na, Li, Xin, Wang, Tianzhi, Nawrot, Barbara
Publicado 2012

Evoking picomolar binding in RNA by a single phosphorodithioate linkage

por Abeydeera, N. Dinuka, Egli, Martin, Cox, Nehemiah, Mercier, Karen, Conde, Jonas Nascimento, Pallan, Pradeep S., Mizurini, Daniella M., Sierant, Malgorzata, Hibti, Fatima-Ezzahra, Hassell, Tom, Wang, Tianzhi, Liu, Feng-Wu, Liu, Hong-Min, Martinez, Carlos, Sood, Anil K., Lybrand, Terry P., Frydman, Chiraz, Monteiro, Robson Q., Gomer, Richard H., Nawrot, Barbara, Yang, Xianbin
Publicado en Nucleic Acids Res (2016)

2’f-OMe-phosphorodithioate modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity

por Wu, Sherry Y., Yang, Xianbin, Gharpure, Kshipra M., Hatakeyama, Hiroto, Egli, Martin, McGuire, Michael H., Nagaraja, Archana S., Miyake, Takahito M., Rupaimoole, Rajesha, Pecot, Chad V., Taylor, Morgan, Pradeep, Sunila, Sierant, Malgorzata, Rodriguez-Aguayo, Cristian, Choi, Hyun J., Previs, Rebecca A., Armaiz-Pena, Guillermo N., Huang, Li, Martinez, Carlos, Hassell, Tom, Ivan, Cristina, Sehgal, Vasudha, Singhania, Richa, Han, Hee-Dong, Su, Chang, Kim, Ji Hoon, Dalton, Heather J., Kowali, Chandra, Keyomarsi, Khandan, McMillan, Nigel A.J., Overwijk, Willem W., Liu, Jinsong, Lee, Ju-Seog, Baggerly, Keith A., Lopez-Berestein, Gabriel, Ram, Prahlad T., Nawrot, Barbara, Sood, Anil K.
Publicado 2014