Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference

RNA interference (RNAi) technology provides a powerful molecular tool to reduce an expression of selected genes in eukaryotic cells. Short interfering RNAs (siRNAs) are the effector molecules that trigger RNAi. Here, we describe siRNAs that discriminate between the wild type and mutant (1174 C→G) al...

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Detaylı Bibliyografya
Asıl Yazarlar: Sierant, Malgorzata, Paduszynska, Alina, Kazmierczak-Baranska, Julia, Nacmias, Benedetta, Sorbi, Sandro, Bagnoli, Silvia, Sochacka, Elzbieta, Nawrot, Barbara
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE-Hindawi Access to Research 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090069/
https://ncbi.nlm.nih.gov/pubmed/21559198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/809218
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