Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference

RNA interference (RNAi) technology provides a powerful molecular tool to reduce an expression of selected genes in eukaryotic cells. Short interfering RNAs (siRNAs) are the effector molecules that trigger RNAi. Here, we describe siRNAs that discriminate between the wild type and mutant (1174 C→G) al...

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Autors principals: Sierant, Malgorzata, Paduszynska, Alina, Kazmierczak-Baranska, Julia, Nacmias, Benedetta, Sorbi, Sandro, Bagnoli, Silvia, Sochacka, Elzbieta, Nawrot, Barbara
Format: Artigo
Idioma:Inglês
Publicat: SAGE-Hindawi Access to Research 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090069/
https://ncbi.nlm.nih.gov/pubmed/21559198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/809218
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