Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference

RNA interference (RNAi) technology provides a powerful molecular tool to reduce an expression of selected genes in eukaryotic cells. Short interfering RNAs (siRNAs) are the effector molecules that trigger RNAi. Here, we describe siRNAs that discriminate between the wild type and mutant (1174 C→G) al...

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Bibliografiska uppgifter
Huvudupphovsmän: Sierant, Malgorzata, Paduszynska, Alina, Kazmierczak-Baranska, Julia, Nacmias, Benedetta, Sorbi, Sandro, Bagnoli, Silvia, Sochacka, Elzbieta, Nawrot, Barbara
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE-Hindawi Access to Research 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090069/
https://ncbi.nlm.nih.gov/pubmed/21559198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/809218
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