Gene Silencing Activity of siRNA Molecules Containing Phosphorodithioate Substitutions

Por Yang, Xianbin, Sierant, Malgorzata, Janicka, Magdalena, Peczek, Lukasz, Martinez, Carlos, Hassell, Tom, Li, Na, Li, Xin, Wang, Tianzhi, Nawrot, Barbara
Publicado em 2012

Dual Roles for Lipolysis and Oxidation in Peroxisome Proliferation-Activator Receptor Responses to Electronegative Low Density Lipoprotein

Por Ziouzenkova, Ouliana, Asatryan, Liana, Sahady, Deanna, Orasanu, Gabriela, Perrey, Stephan, Cutak, Benjamin, Hassell, Tom, Akiyama, Taro E., Berger, Joel P., Sevanian, Alex, Plutzky, Jorge
Publicado no J Biol Chem (2003)

Evoking picomolar binding in RNA by a single phosphorodithioate linkage

Por Abeydeera, N. Dinuka, Egli, Martin, Cox, Nehemiah, Mercier, Karen, Conde, Jonas Nascimento, Pallan, Pradeep S., Mizurini, Daniella M., Sierant, Malgorzata, Hibti, Fatima-Ezzahra, Hassell, Tom, Wang, Tianzhi, Liu, Feng-Wu, Liu, Hong-Min, Martinez, Carlos, Sood, Anil K., Lybrand, Terry P., Frydman, Chiraz, Monteiro, Robson Q., Gomer, Richard H., Nawrot, Barbara, Yang, Xianbin
Publicado no Nucleic Acids Res (2016)

2’f-OMe-phosphorodithioate modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity

Por Wu, Sherry Y., Yang, Xianbin, Gharpure, Kshipra M., Hatakeyama, Hiroto, Egli, Martin, McGuire, Michael H., Nagaraja, Archana S., Miyake, Takahito M., Rupaimoole, Rajesha, Pecot, Chad V., Taylor, Morgan, Pradeep, Sunila, Sierant, Malgorzata, Rodriguez-Aguayo, Cristian, Choi, Hyun J., Previs, Rebecca A., Armaiz-Pena, Guillermo N., Huang, Li, Martinez, Carlos, Hassell, Tom, Ivan, Cristina, Sehgal, Vasudha, Singhania, Richa, Han, Hee-Dong, Su, Chang, Kim, Ji Hoon, Dalton, Heather J., Kowali, Chandra, Keyomarsi, Khandan, McMillan, Nigel A.J., Overwijk, Willem W., Liu, Jinsong, Lee, Ju-Seog, Baggerly, Keith A., Lopez-Berestein, Gabriel, Ram, Prahlad T., Nawrot, Barbara, Sood, Anil K.
Publicado em 2014