Proteasome Inhibitors in the Treatment of Multiple Myeloma

Por Shah, Jatin J., Orlowski, Robert Z.
Publicado no Leukemia (2009)

Bortezomib and EGCG: no green tea for you?

Por Shah, Jatin J., Kuhn, Deborah J., Orlowski, Robert Z.
Publicado em 2009

Role of combination bortezomib and pegylated liposomal doxorubicin in the management of relapsed and/or refractory multiple myeloma

Por Shah, Jatin J, Orlowski, Robert Z, Thomas, Sheeba K
Publicado em 2009

Novel Approaches to Treatment of “Double-Refractory” Multiple Myeloma

Por Lee, Hans C., Shah, Jatin J., Orlowski, Robert Z.
Publicado em 2013

Changes in pain and other symptoms in patients with painful multiple myeloma-related vertebral fracture treated with kyphoplasty or vertebroplasty

Por Mendoza, Tito R., Koyyalagunta, Dhanalakshmi, Burton, Allen W., Thomas, Sheeba K., Phan, My-Hanh V., Giralt, Sergio A., Shah, Jatin J., Cleeland, Charles S.
Publicado em 2012

Pembrolizumab (MK-3475) in combination with lenalidomide and low-dose dexamethasone for relapsed/refractory multiple myeloma (RRMM): KEYNOTE-023

Por Mateos, Maria-Victoria, Siegel, David, Shah, Jatin J, Reece, Donna, Avigan, David, Orlowski, Robert, Ge, Yang, Balakumaran, Arun, Marinello, Patricia, Miguel, Jesus San
Publicado no J Immunother Cancer (2015)

Evidence of a Role for Activation of Wnt/β-Catenin Signaling in the Resistance of Plasma Cells to Lenalidomide

Por Bjorklund, Chad C., Ma, Wencai, Wang, Zhi-Qiang, Davis, R. Eric, Kuhn, Deborah J., Kornblau, Steven M., Wang, Michael, Shah, Jatin J., Orlowski, Robert Z.
Publicado em 2011

Thymidine phosphorylase exerts complex effects on bone resorption and formation in myeloma

Por Liu, Huan, Liu, Zhiqiang, Du, Juan, He, Jin, Lin, Pei, Amini, Behrang, Starbuck, Michael W., Novane, Nora, Shah, Jatin J., Davis, Richard E., Hou, Jian, Gagel, Robert F., Yang, Jing
Publicado no Sci Transl Med (2016)

Evidence of a Role for CD44 and Cell Adhesion in Mediating Resistance to Lenalidomide in Multiple Myeloma: Therapeutic Implications

Por Bjorklund, Chad C., Baladandayuthapani, Veerabhadran, Lin, Heather Y., Jones, Richard J., Kuiatse, Isere, Wang, Hua, Yang, Jing, Shah, Jatin J., Thomas, Sheeba K., Wang, Michael, Weber, Donna M., Orlowski, Robert Z.
Publicado em 2013

Lenalidomide, Thalidomide, and Pomalidomide Reactivate the Epstein-Barr Virus Lytic Cycle Through Phosphoinositide 3-kinase Signaling and Ikaros Expression

Por Jones, Richard J., Iempridee, Tawin, Wang, Xiaobin, Lee, Hans C., Mertz, Janet E., Kenney, Shannon C., Lin, Heather C., Baladandayuthapani, Veerabhadran, Dawson, Christopher W., Shah, Jatin J., Weber, Donna M., Orlowski, Robert Z.
Publicado no Clin Cancer Res (2016)

Blockade of interleukin-6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma

Por Hunsucker, Sally A., Magarotto, Valeria, Kuhn, Deborah J., Kornblau, Steven M., Wang, Michael, Weber, Donna M., Thomas, Sheeba K., Shah, Jatin J., Voorhees, Peter M., Xie, Hong, Cornfeld, Mark, Nemeth, Jeffrey A., Orlowski, Robert Z.
Publicado em 2011

Impact Of t(11;14)(q13;q32) On The Outcome Of Autologous Hematopoietic Cell Transplantation In Multiple Myeloma

Por Sasaki, Koji, Lu, Gary, Saliba, Rima M., Bashir, Qaiser, Hosing, Chitra, Popat, Uday, Shah, Nina, Parmar, Simrit, Dinh, Yvonne, Ahmed, Sairah, Shpall, Elizabeth J., Kebriaei, Partow, Shah, Jatin J., Orlowski, Robert Z, Champlin, Richard, Qazilbash, Muzaffar H.
Publicado em 2013

Outcomes Among High-Risk and Standard-Risk Multiple Myeloma Patients Treated with High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation

Por Kazmi, Syed M., Nusrat, Maliha, Gunaydin, Hilal, Cornelison, Amanda M., Shah, Nina, Kebriaei, Partow, Nieto, Yago, Parmar, Simrit, Popat, Uday R., Oran, Betul, Shah, Jatin J., Orlowski, Robert Z., Champlin, Richard E., Qazilbash, Muzaffar H., Bashir, Qaiser
Publicado no Clin Lymphoma Myeloma Leuk (2015)

Carfilzomib, pomalidomide, and dexamethasone for relapsed or refractory myeloma

Por Shah, Jatin J., Stadtmauer, Edward A., Abonour, Rafat, Cohen, Adam D., Bensinger, William I., Gasparetto, Cristina, Kaufman, Jonathan L., Lentzsch, Suzanne, Vogl, Dan T., Gomes, Christina L., Pascucci, Natalia, Smith, David D., Orlowski, Robert Z., Durie, Brian G. M.
Publicado no Blood (2015)

Targeting the Spleen Tyrosine Kinase with Fostamatinib as a Strategy Against Waldenström’s Macroglobulinemia

Por Kuiatse, Isere, Baladandayuthapani, Veerabhadran, Lin, Heather Y., Thomas, Sheeba K., Bjorklund, Chad C., Weber, Donna M., Wang, Michael, Shah, Jatin J., Zhang, Xing-Ding, Jones, Richard J., Ansell, Stephen M., Yang, Guang, Treon, Steven P., Orlowski, Robert Z.
Publicado no Clin Cancer Res (2015)

Prolonged survival with longer duration of maintenance lenalidomide after autologous hematopoietic stem cell transplantation for multiple myeloma

Por Mian, Idrees, Milton, Denái R., Shah, Nina, Nieto, Yago, Popat, Uday R., Kebriaei, Partow, Parmar, Simrit, Oran, Betul, Shah, Jatin J., Manasanch, Elisabet E., Orlowski, Robert Z., Shpall, Elizabeth J., Champlin, Richard E., Qazilbash, Muzaffar H., Bashir, Qaiser
Publicado no Cancer (2016)

A Randomized Phase II Trial of a Preparative Regimen of Bortezomib, High Dose Melphalan, Arsenic Trioxide and Ascorbic Acid

Por Sharma, Manish, Khan, Hassan, Thall, Peter F, Orlowski, Robert Z, Bassett, Roland L, Shah, Nina, Bashir, Qaiser, Parmar, Simrit, Wang, Michael, Shah, Jatin J, Hosing, Chitra M, Popat, Uday R, Giralt, Sergio A, Champlin, Richard E, Qazilbash, Muzaffar H
Publicado em 2011

Phase I/II trial of lenalidomide and high dose melphalan with autologous stem cell transplantation for relapsed myeloma

Por Shah, Nina, Thall, Peter F., Fox, Patricia S., Bashir, Qaiser, Shah, Jatin J., Parmar, Simrit, Lin, Pei, Kebriaei, Partow, Nieto, Yago, Popat, Uday R., Hosing, Chitra M., Cornelison, Amanda, Shpall, Elizabeth J., Orlowski, Robert Z., Champlin, Richard E., Qazilbash, Muzaffar H.
Publicado no Leukemia (2015)

Targeting the insulin-like growth factor-1 receptor to overcome bortezomib resistance in preclinical models of multiple myeloma

Por Kuhn, Deborah J., Berkova, Zuzana, Jones, Richard J., Woessner, Richard, Bjorklund, Chad C., Ma, Wencai, Davis, R. Eric, Lin, Pei, Wang, Hua, Madden, Timothy L., Wei, Caimiao, Baladandayuthapani, Veerabhadran, Wang, Michael, Thomas, Sheeba K., Shah, Jatin J., Weber, Donna M., Orlowski, Robert Z.
Publicado em 2012

Evidence of a Role for the Novel Zinc-finger Transcription Factor ZKSCAN3 in Modulating Cyclin D2 Expression in Multiple Myeloma

Por Yang, Lin, Wang, Hua, Kornblau, Steven M., Graber, David A., Zhang, Nianxian, Matthews, Jairo A., Wang, Michael, Weber, Donna M., Thomas, Sheeba K., Shah, Jatin J., Zhang, Li, Lu, Gary, Zhao, Ming, Mudasani, Ramya, Yoo, Suk-Young, Baggerly, Keith A., Orlowski, Robert Z.
Publicado em 2010