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Thymidine phosphorylase exerts complex effects on bone resorption and formation in myeloma

Myelomatous bone disease is characterized by the development of lytic bone lesions and a concomitant reduction in bone formation, leading to chronic bone pain and fractures. To understand the underlying mechanism, we investigated the contribution of myeloma-expressed thymidine phosphorylase (TP) to...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Transl Med
Main Authors: Liu, Huan, Liu, Zhiqiang, Du, Juan, He, Jin, Lin, Pei, Amini, Behrang, Starbuck, Michael W., Novane, Nora, Shah, Jatin J., Davis, Richard E., Hou, Jian, Gagel, Robert F., Yang, Jing
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109917/
https://ncbi.nlm.nih.gov/pubmed/27559096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad8949
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