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Thymidine phosphorylase exerts complex effects on bone resorption and formation in myeloma
Myelomatous bone disease is characterized by the development of lytic bone lesions and a concomitant reduction in bone formation, leading to chronic bone pain and fractures. To understand the underlying mechanism, we investigated the contribution of myeloma-expressed thymidine phosphorylase (TP) to...
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| Publicado en: | Sci Transl Med |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5109917/ https://ncbi.nlm.nih.gov/pubmed/27559096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad8949 |
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