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Thymidine Phosphorylase in Cancer; Enemy or Friend?

Thymidine phosphorylase (TP) is a nucleoside metabolism enzyme that plays an important role in the pyrimidine pathway.TP catalyzes the conversion of thymidine to thymine and 2-deoxy-α-D-ribose-1-phosphate (dRib-1-P). Although this reaction is reversible, the main metabolic function of TP is cataboli...

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Bibliografiske detaljer
Udgivet i:Cancer Microenviron
Main Authors: Elamin, Yasir Y., Rafee, Shereen, Osman, Nemer, O′Byrne, Kenneth J., Gately, Kathy
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842186/
https://ncbi.nlm.nih.gov/pubmed/26298314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12307-015-0173-y
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