Bringing influenza vaccines into the 21st century

Por Settembre, Ethan C, Dormitzer, Philip R, Rappuoli, Rino
Publicado em 2014

Atomic model of an infectious rotavirus particle

Por Settembre, Ethan C, Chen, James Z, Dormitzer, Philip R, Grigorieff, Nikolaus, Harrison, Stephen C
Publicado em 2011

Reference antigen-free and antibody-free LTD-IDMS assay for influenza H7N9 vaccine in vitro potency determination

Por Morgenstern, Keith, Xie, Yuhong, Palladino, Giuseppe, Barr, John R., Settembre, Ethan C., Williams, Tracie L., Wen, Yingxia
Publicado no Vaccine (2018)

Limited Tryptic Digestion-Isotope Dilution Mass Spectrometry (LTD-IDMS): A Reagent-Free Analytical Assay To Quantify Hemagglutinin of A(H5N1) Vaccine Material

Por Cooper, Hans C., Xie, Yuhong, Palladino, Giuseppe, Barr, John R., Settembre, Ethan C., Wen, Yingxia, Williams, Tracie L.
Publicado no Anal Chem (2020)

Antigenic characterization of influenza viruses produced using synthetic DNA and novel backbones

Por Suphaphiphat, Pirada, Whittaker, Lynne, De Souza, Ivna, Daniels, Rodney S., Dormitzer, Philip R., McCauley, John W., Settembre, Ethan C.
Publicado no Vaccine (2016)

Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM

Por Chen, James Z., Settembre, Ethan C., Aoki, Scott T., Zhang, Xing, Bellamy, A. Richard, Dormitzer, Philip R., Harrison, Stephen C., Grigorieff, Nikolaus
Publicado em 2009

Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles

Por Estrozi, Leandro F., Settembre, Ethan C., Goret, Gaël, McClain, Brian, Zhang, Xing, Chen, James Z., Grigorieff, Nikolaus, Harrison, Stephen C.
Publicado em 2012

Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody

Por Raymond, Donald D., Bajic, Goran, Ferdman, Jack, Suphaphiphat, Pirada, Settembre, Ethan C., Moody, M. Anthony, Schmidt, Aaron G., Harrison, Stephen C.
Publicado no Proc Natl Acad Sci U S A (2018)

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

Por Swanson, Kurt A., Settembre, Ethan C., Shaw, Christine A., Dey, Antu K., Rappuoli, Rino, Mandl, Christian W., Dormitzer, Philip R., Carfi, Andrea
Publicado em 2011

Active-site models for complexes of quinolinate synthase with substrates and intermediates

Por Soriano, Erika V., Zhang, Yang, Colabroy, Keri L., Sanders, Jennie M., Settembre, Ethan C., Dorrestein, Pieter C., Begley, Tadhg P., Ealick, Steven E.
Publicado em 2013

Glycal Formation in Crystals of Uridine Phosphorylase

Por Paul, Debamita, O'Leary, Seán E., Rajashankar, Kanagalaghatta, Bu, Weiming, Toms, Angela, Settembre, Ethan C., Sanders, Jennie M., Begley, Tadhg P., Ealick, Steven E.
Publicado em 2010

Structure of Herpes Simplex Virus Glycoprotein D Bound to the Human Receptor Nectin-1

Por Di Giovine, Paolo, Settembre, Ethan C., Bhargava, Arjun K., Luftig, Micah A., Lou, Huan, Cohen, Gary H., Eisenberg, Roselyn J., Krummenacher, Claude, Carfi, Andrea
Publicado em 2011

Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH

Por Surdo, Paola Lo, Bottomley, Matthew J, Calzetta, Alessandra, Settembre, Ethan C, Cirillo, Agostino, Pandit, Shilpa, Ni, Yan G, Hubbard, Brian, Sitlani, Ayesha, Carfí, Andrea
Publicado em 2011

An Innovative Pseudotypes-Based Enzyme-Linked Lectin Assay for the Measurement of Functional Anti-Neuraminidase Antibodies

Por Prevato, Marua, Cozzi, Roberta, Pezzicoli, Alfredo, Taddei, Anna Rita, Ferlenghi, Ilaria, Nandi, Avishek, Montomoli, Emanuele, Settembre, Ethan C., Bertholet, Sylvie, Bonci, Alessandra, Legay, Francois
Publicado no PLoS One (2015)

Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody

Por Chandramouli, Sumana, Ciferri, Claudio, Nikitin, Pavel A., Caló, Stefano, Gerrein, Rachel, Balabanis, Kara, Monroe, James, Hebner, Christy, Lilja, Anders E., Settembre, Ethan C., Carfi, Andrea
Publicado no Nat Commun (2015)

Expression and Characterization of Recombinant, Tetrameric and Enzymatically Active Influenza Neuraminidase for the Setup of an Enzyme-Linked Lectin-Based Assay

Por Prevato, Marua, Ferlenghi, Ilaria, Bonci, Alessandra, Uematsu, Yasushi, Anselmi, Giulia, Giusti, Fabiola, Bertholet, Sylvie, Legay, Francois, Telford, John Laird, Settembre, Ethan C., Maione, Domenico, Cozzi, Roberta
Publicado no PLoS One (2015)

Intra-Seasonal Antibody Repertoire Analysis of a Patient Immunized with an MF59(®)-adjuvanted Pandemic 2009 H1N1 Vaccine

Por Ferdman, Jack, Palladino, Giuseppe, Liao, Hua-Xin, Moody, M. Anthony, Kepler, Thomas B., Giudice, Giuseppe Del, Dormitzer, Philip R., Harrison, Stephen C, Settembre, Ethan C., Suphaphiphat, Pirada
Publicado no Vaccine (2018)

Antigenic Characterization of the HCMV gH/gL/gO and Pentamer Cell Entry Complexes Reveals Binding Sites for Potently Neutralizing Human Antibodies

Por Ciferri, Claudio, Chandramouli, Sumana, Leitner, Alexander, Donnarumma, Danilo, Cianfrocco, Michael A., Gerrein, Rachel, Friedrich, Kristian, Aggarwal, Yukti, Palladino, Giuseppe, Aebersold, Ruedi, Norais, Nathalie, Settembre, Ethan C., Carfi, Andrea
Publicado no PLoS Pathog (2015)

Saccharomyces cerevisiae-derived virus-like particle parvovirus B19 vaccine elicits binding and neutralizing antibodies in a mouse model for sickle cell disease

Por Penkert, Rhiannon R., Young, Neal S., Surman, Sherri L., Sealy, Robert E., Rosch, Jason, Dormitzer, Philip R., Settembre, Ethan C., Chandramouli, Sumana, Wong, Susan, Hankins, Jane S., Hurwitz, Julia L.
Publicado no Vaccine (2017)

Structural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes

Por Ciferri, Claudio, Chandramouli, Sumana, Donnarumma, Danilo, Nikitin, Pavel A., Cianfrocco, Michael A., Gerrein, Rachel, Feire, Adam L., Barnett, Susan W., Lilja, Anders E., Rappuoli, Rino, Norais, Nathalie, Settembre, Ethan C., Carfi, Andrea
Publicado no Proc Natl Acad Sci U S A (2015)