Structure of Herpes Simplex Virus Glycoprotein D Bound to the Human Receptor Nectin-1

Binding of herpes simplex virus (HSV) glycoprotein D (gD) to a cell surface receptor is required to trigger membrane fusion during entry into host cells. Nectin-1 is a cell adhesion molecule and the main HSV receptor in neurons and epithelial cells. We report the structure of gD bound to nectin-1 de...

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Hauptverfasser: Di Giovine, Paolo, Settembre, Ethan C., Bhargava, Arjun K., Luftig, Micah A., Lou, Huan, Cohen, Gary H., Eisenberg, Roselyn J., Krummenacher, Claude, Carfi, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182920/
https://ncbi.nlm.nih.gov/pubmed/21980294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002277
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