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Glycal Formation in Crystals of Uridine Phosphorylase

Uridine phosphorylase is a key enzyme in the pyrimidine salvage pathway. This enzyme catalyzes the reversible phosphorolysis of uridine to uracil and ribose 1-phosphate (or 2′-deoxyuridine to 2′-deoxyribose 1-phosphate). Here we report the structure of hexameric Escherichia coli uridine phosphorylas...

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Autors principals: Paul, Debamita, O'Leary, Seán E., Rajashankar, Kanagalaghatta, Bu, Weiming, Toms, Angela, Settembre, Ethan C., Sanders, Jennie M., Begley, Tadhg P., Ealick, Steven E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857653/
https://ncbi.nlm.nih.gov/pubmed/20364833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902073b
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