The crystal structure and activity of a putative trypanosomal nucleoside phosphorylase reveal it to be a homodimeric uridine phosphorylase

Purine nucleoside phosphorylases and uridine phosphorylases are closely related enzymes involved in purine and pyrimidine salvage, respectively, which catalyze the removal of the ribosyl moiety from nucleosides so that the nucleotide base may be recycled. Parasitic protozoa generally are incapable o...

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Detaylı Bibliyografya
Asıl Yazarlar: Larson, Eric T., Mudeppa, Devaraja G., Gillespie, J. Robert, Mueller, Natascha, Napuli, Alberto J., Arif, Jennifer A., Ross, Jenni, Arakaki, Tracy L., Lauricella, Angela, DeTitta, George, Luft, Joseph, Zucker, Frank, Verlinde, Christophe L. M. J., Fan, Erkang, Van Voorhis, Wesley C., Buckner, Frederick S., Rathod, Pradipsinh K., Hol, Wim G. J., Merritt, Ethan A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844865/
https://ncbi.nlm.nih.gov/pubmed/20070944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.013
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