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Active-site models for complexes of quinolinate synthase with substrates and intermediates

Quinolinate synthase (QS) catalyzes the condensation of iminoaspartate and dihydroxyacetone phosphate to form quinolinate, the universal precursor for the de novo biosynthesis of nicotinamide adenine dinucleotide. QS has been difficult to characterize owing either to instability or lack of activity...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Soriano, Erika V., Zhang, Yang, Colabroy, Keri L., Sanders, Jennie M., Settembre, Ethan C., Dorrestein, Pieter C., Begley, Tadhg P., Ealick, Steven E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: International Union of Crystallography 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760129/
https://ncbi.nlm.nih.gov/pubmed/23999292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S090744491301247X
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