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Active-site models for complexes of quinolinate synthase with substrates and intermediates
Quinolinate synthase (QS) catalyzes the condensation of iminoaspartate and dihydroxyacetone phosphate to form quinolinate, the universal precursor for the de novo biosynthesis of nicotinamide adenine dinucleotide. QS has been difficult to characterize owing either to instability or lack of activity...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
International Union of Crystallography
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760129/ https://ncbi.nlm.nih.gov/pubmed/23999292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S090744491301247X |
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