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Crystal structures of the iron-sulfur cluster dependent quinolinate synthase in complex with dihydroxyacetone phosphate, iminoaspartate analogs, and quinolinate
The quinolinate synthase of prokaryotes and photosynthetic eukaryotes, NadA, contains a [4Fe-4S] cluster with unknown function. We report crystal structures of Pyrococcus horikoshii NadA in complex with dihydroxyacetone phosphate (DHAP), iminoaspartate analogs, and quinolinate. DHAP adopts a nearly...
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| Udgivet i: | Biochemistry |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7775720/ https://ncbi.nlm.nih.gov/pubmed/27404889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00626 |
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