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Crystal structures of the iron-sulfur cluster dependent quinolinate synthase in complex with dihydroxyacetone phosphate, iminoaspartate analogs, and quinolinate

The quinolinate synthase of prokaryotes and photosynthetic eukaryotes, NadA, contains a [4Fe-4S] cluster with unknown function. We report crystal structures of Pyrococcus horikoshii NadA in complex with dihydroxyacetone phosphate (DHAP), iminoaspartate analogs, and quinolinate. DHAP adopts a nearly...

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Bibliografiska uppgifter
I publikationen:Biochemistry
Huvudupphovsmän: Fenwick, Michael K., Ealick, Steven E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775720/
https://ncbi.nlm.nih.gov/pubmed/27404889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00626
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