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Saccharomyces cerevisiae THI4p is a suicidal thiamin thiazole synthase
Thiamin pyrophosphate 1 (Figure 1A) is an essential cofactor in all living systems(1). Its biosynthesis involves the separate syntheses of the pyrimidine 2 and thiazole 3 precursors, which are then coupled(2). Two biosynthetic routes to the thiamin thiazole have been identified. In prokaryotes, five...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205460/ https://ncbi.nlm.nih.gov/pubmed/22031445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10503 |
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