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Domain Organization in Candida glabrata THI6, a Bifunctional Enzyme Required for Thiamin Biosynthesis in Eukaryotes
THI6 is a bifunctional enzyme found in the thiamin biosynthetic pathway in eukaryotes. The N-terminal domain of THI6 catalyzes the ligation of the thiamin thiazole and pyrimidine moieties to form thiamin phosphate and the C-terminal domain catalyzes the phosphorylation of 4-methyl-5-hydroxyethylthia...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2996881/ https://ncbi.nlm.nih.gov/pubmed/20968298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101008u |
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