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Biosynthesis of the thiamin thiazole in Bacillus subtilis: Identification of the product of the thiazole synthase-catalyzed reaction

In this paper, we describe an optimized reconstitution of the thiamin thiazole synthase (ThiG) catalyzed reaction and demonstrate that the enzymatic product is an unanticipated dearomatized thiazole tautomer.

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Detaylı Bibliyografya
Asıl Yazarlar: Hazra, Amrita, Chatterjee, Abhishek, Begley, Tadhg P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765510/
https://ncbi.nlm.nih.gov/pubmed/19216519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja806752h
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