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Biosynthesis of the thiamin thiazole in Bacillus subtilis: Identification of the product of the thiazole synthase-catalyzed reaction

In this paper, we describe an optimized reconstitution of the thiamin thiazole synthase (ThiG) catalyzed reaction and demonstrate that the enzymatic product is an unanticipated dearomatized thiazole tautomer.

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hazra, Amrita, Chatterjee, Abhishek, Begley, Tadhg P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765510/
https://ncbi.nlm.nih.gov/pubmed/19216519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja806752h
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