A Missing Enzyme in Thiamin Thiazole Biosynthesis: Identification of TenI as a Thiazole Tautomerase

In many bacteria tenI is found clustered with genes involved in thiamin thiazole biosynthesis. However, while TenI shows high sequence similarity with thiamin phosphate synthase, the purified protein has no thiamin phosphate synthase activity and the role of this enzyme in thiamin biosynthesis remai...

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Bibliographic Details
Main Authors: Hazra, Amrita B., Han, Ying, Chatterjee, Abhishek, Zhang, Yang, Lai, Rung-Yi, Ealick, Steven E., Begley, Tadhg P.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116082/
https://ncbi.nlm.nih.gov/pubmed/21534620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1110514
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