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A Missing Enzyme in Thiamin Thiazole Biosynthesis: Identification of TenI as a Thiazole Tautomerase

In many bacteria tenI is found clustered with genes involved in thiamin thiazole biosynthesis. However, while TenI shows high sequence similarity with thiamin phosphate synthase, the purified protein has no thiamin phosphate synthase activity and the role of this enzyme in thiamin biosynthesis remai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hazra, Amrita B., Han, Ying, Chatterjee, Abhishek, Zhang, Yang, Lai, Rung-Yi, Ealick, Steven E., Begley, Tadhg P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116082/
https://ncbi.nlm.nih.gov/pubmed/21534620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1110514
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