ω- versus (ω-1)-hydroxylation: Cytochrome P450 4B1 sterics make the call

Por Scott, Emily E.
Publicado no J Biol Chem (2017)

Structural and functional effects of cytochrome b(5) interactions with human cytochrome P450 enzymes

Por Bart, Aaron G., Scott, Emily E.
Publicado no J Biol Chem (2017)

CYTOCHROME P450 17A1 STRUCTURES WITH PROSTATE CANCER DRUGS ABIRATERONE AND TOK-001

Por DeVore, Natasha M., Scott, Emily E.
Publicado em 2012

Nicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Binding and Access Channel in Human Cytochrome P450 2A6 and 2A13 Enzymes

Por DeVore, Natasha M., Scott, Emily E.
Publicado em 2012

Expression, purification, crystallization and preliminary X-ray studies of a prolyl-4-hydroxylase protein from Bacillus anthracis

Por Miller, Megen A., Scott, Emily E., Limburg, Julian
Publicado em 2008

CRYSTAL STRUCTURE OF PROLYL 4-HYDROXYLASE FROM BACILLUS ANTHRACIS

Por Culpepper, Megen A., Scott, Emily E., Limburg, Julian
Publicado em 2010

Evaluation of Inhibition Selectivity for Human Cytochrome P450 2A Enzymes

Por Stephens, Eva S., Walsh, Agnes A., Scott, Emily E.
Publicado em 2012

Substrate-modulated Cytochrome P450 17A1 and Cytochrome b(5) Interactions Revealed by NMR

Por Estrada, D. Fernando, Laurence, Jennifer S., Scott, Emily E.
Publicado em 2013

Cytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMR

Por Estrada, D. Fernando, Laurence, Jennifer S., Scott, Emily E.
Publicado no J Biol Chem (2016)

p-Dimethylaminocinnamaldehyde Derivatization for Colorimetric Detection and HPLC-UV/Vis-MS/MS Identification of Indoles

Por Porubsky, Patrick R., Scott, Emily E., Williams, Todd D.
Publicado em 2008

Structures of Human Cytochrome P-450 2E1: INSIGHTS INTO THE BINDING OF INHIBITORS AND BOTH SMALL MOLECULAR WEIGHT AND FATTY ACID SUBSTRATES

Por Porubsky, Patrick R., Meneely, Kathleen M., Scott, Emily E.
Publicado em 2008

Human Cytochrome P450 2E1 Structures with Fatty Acid Analogs Reveal a Previously Unobserved Binding Mode

Por Porubsky, Patrick R., Battaile, Kevin P., Scott, Emily E.
Publicado em 2010

Human Cytochrome P450 1A1 Structure and Utility in Understanding Drug and Xenobiotic Metabolism

Por Walsh, Agnes A., Szklarz, Grazyna D., Scott, Emily E.
Publicado em 2013

Human Cytochrome P450 17A1 Conformational Selection: MODULATION BY LIGAND AND CYTOCHROME b(5)

Por Estrada, D. Fernando, Skinner, Andria L., Laurence, Jennifer S., Scott, Emily E.
Publicado em 2014

Structural Insights into the Function of Steroidogenic Cytochrome P450 17A1

Por Yadav, Rahul, Petrunak, Elyse M., Estrada, D. Fernando, Scott, Emily E.
Publicado no Mol Cell Endocrinol (2016)

Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1

Por Petrunak, Elyse M., Rogers, Steven A., Aubé, Jeffrey, Scott, Emily E.
Publicado no Drug Metab Dispos (2017)

Expression, purification, crystallization and preliminary X-ray studies of histamine dehydrogenase from Nocardioides simplex

Por Reed, Timothy M., Hirakawa, Hidehiko, Mure, Minae, Scott, Emily E., Limburg, Julian
Publicado em 2008

KEY RESIDUES CONTROLLING PHENACETIN METABOLISM BY HUMAN CYTOCHROME P450 2A ENZYMES(†)

Por DeVore, Natasha M., Smith, Brian D., Urban, Michael J., Scott, Emily E.
Publicado em 2008

Structures of Human Steroidogenic Cytochrome P450 17A1 with Substrates

Por Petrunak, Elyse M., DeVore, Natasha M., Porubsky, Patrick R., Scott, Emily E.
Publicado no J Biol Chem (2014)

Benzylmorpholine Analogs as Selective Inhibitors of Lung Cytochrome P450 2A13 for the Chemoprevention of Lung Cancer in Tobacco Users

Por Blake, Linda C., Roy, Anuradha, Neul, David, Schoenen, Frank J., Aubé, Jeffrey, Scott, Emily E.
Publicado em 2013