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Structural and functional effects of cytochrome b(5) interactions with human cytochrome P450 enzymes

The small heme-containing protein cytochrome b(5) can facilitate, inhibit, or have no effect on cytochrome P450 catalysis, often in a P450-dependent and substrate-dependent manner that is not well understood. Herein, solution NMR was used to identify b(5) residues interacting with different human dr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bart, Aaron G., Scott, Emily E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743060/
https://ncbi.nlm.nih.gov/pubmed/29079577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000220
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