Effects of Membrane Mimetics on Cytochrome P450-Cytochrome b(5) Interactions Characterized by NMR Spectroscopy

Mammalian cytochrome P450 (P450) is a membrane-bound monooxygenase whose catalytic activities require two electrons to be sequentially delivered from its redox partners: cytochrome b(5) (cytb(5)) and cytochrome P450 reductase, both of which are membrane proteins. Although P450 functional activities...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Zhang, Meng, Huang, Rui, Im, Sang-Choul, Waskell, Lucy, Ramamoorthy, Ayyalusamy
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432288/
https://ncbi.nlm.nih.gov/pubmed/25795780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.597096
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