Dynamic Interaction Between Membrane-Bound Full-Length Cytochrome P450 and Cytochrome b(5) Observed by Solid-State NMR Spectroscopy

Microsomal monoxygenase enzymes of the cytochrome-P450 family are found in all biological kingdoms, and play a central role in the breakdown of metabolic as well as xenobiotic, toxic and 70% of the drugs in clinical use. Full-length cytochrome-b5 has been shown to be important for the catalytic acti...

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Huvudupphovsmän: Yamamoto, Kazutoshi, Dürr, Ulrich H. N., Xu, Jiadi, Im, Sang-Choul, Waskell, Lucy, Ramamoorthy, Ayyalusamy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756332/
https://ncbi.nlm.nih.gov/pubmed/23985776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02538
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