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Dynamic Interaction Between Membrane-Bound Full-Length Cytochrome P450 and Cytochrome b(5) Observed by Solid-State NMR Spectroscopy
Microsomal monoxygenase enzymes of the cytochrome-P450 family are found in all biological kingdoms, and play a central role in the breakdown of metabolic as well as xenobiotic, toxic and 70% of the drugs in clinical use. Full-length cytochrome-b5 has been shown to be important for the catalytic acti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3756332/ https://ncbi.nlm.nih.gov/pubmed/23985776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02538 |
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