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Probing the Transmembrane Structure and Topology of Microsomal Cytochrome-P450 by Solid-State NMR on Temperature-Resistant Bicelles

Though the importance of high-resolution structure and dynamics of membrane proteins has been well recognized, optimizing sample conditions to retain the native-like folding and function of membrane proteins for Nuclear Magnetic Resonance (NMR) or X-ray measurements has been a major challenge. While...

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Autors principals: Yamamoto, Kazutoshi, Gildenberg, Melissa, Ahuja, Shivani, Im, Sang-Choul, Pearcy, Paige, Waskell, Lucy, Ramamoorthy, Ayyalusamy
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757361/
https://ncbi.nlm.nih.gov/pubmed/23989972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02556
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