Transmembrane Interactions of Full-length Mammalian Bitopic Cytochrome-P450-Cytochrome-b(5) Complex in Lipid Bilayers Revealed by Sensitivity-Enhanced Dynamic Nuclear Polarization Solid-state NMR Spectroscopy

The dynamic protein-protein and protein-ligand interactions of integral bitopic membrane proteins with a single membrane-spanning helix play a plethora of vital roles in the cellular processes associated with human health and diseases, including signaling and enzymatic catalysis. While an increasing...

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Publicat a:Sci Rep
Autors principals: Yamamoto, Kazutoshi, Caporini, Marc A., Im, Sang-Choul, Waskell, Lucy, Ramamoorthy, Ayyalusamy
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482851/
https://ncbi.nlm.nih.gov/pubmed/28646173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04219-1
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