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Evaluation of Inhibition Selectivity for Human Cytochrome P450 2A Enzymes
Cytochrome P450 (P450) enzymes are mixed-function oxidases that catalyze the metabolism of xenobiotics and endogenous biochemicals. Selective inhibitors are needed to accurately distinguish the contributions of individual P450 enzymes in the metabolism of drugs and the activation of procarcinogens i...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422547/ https://ncbi.nlm.nih.gov/pubmed/22696418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.045161 |
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