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Inhibition of Cytochrome P450 Enzymes by Quinones and Anthraquinones

In silico docking studies and quantitative structure–activity relationship analysis of a number of in-house cytochrome P450 inhibitors have revealed important structural characteristics that are required for a molecule to function as a good inhibitor of P450 enzymes 1A1, 1A2, 2B1, and/or 2A6. These...

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Bibliografiske detaljer
Udgivet i:Chem Res Toxicol
Main Authors: Sridhar, Jayalakshmi, Liu, Jiawang, Foroozesh, Maryam, Klein Stevens, Cheryl L.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461952/
https://ncbi.nlm.nih.gov/pubmed/22185593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx2004163
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